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In this paper, the domestic and international demand and development trend of clinical diagnostic radionuclides are analyzed, and the medium and high-energy cyclotrons, adequate and systematic facilities, and preparation techniques required for the production of medical radionuclides based on solid targets are introduced. This paper focuses on the research and development carried out by some important medical institutions and scientific research institutes in China over the years in the aspects of medium and high-energy cyclotrons, beam transmission lines, high-power irradiation target stations and new medical isotope production processes etc. It also looks forward to some new directions for the development of medical radionuclides in China during the 14th Five-Year Plan period.
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Abastract:Objective To explore the pathogenic bacteria distribution and drug resistance of otitis media in preschool children.Methods Children with otitis media during January 2012 to December 2015 were selected. Ear discharge was taken for common pathogenic bacteria isolation and culture. The drug sensitivity was tested.Results In 200 strains of pathogenic bacteria isolated, 156 (78.0%) strains were Gram-positive cocci, mainly beingStreptococcus pneumoniae,Staphylococcus aureus; 38 (19.0%) strains were Gram-negative bacilli, mainly beingPseudomonas aeruginosa; 6 (3.0%) strains were monilia. Streptococcus pneumoniae had high rate of resistance to erythromycin, tetracycline, clindamycin and sulfamethoxazole, and low rate of resistance to penicillin.Staphylococcus aureus had high rate of resistance to penicillin, and had not found resistance to vancomycin, linezolid and daptomycin. In routine monitoring of 12 kinds of antimicrobial agents, the overall drug resistance of Pseudomonas aeruginosa was low, and the resistance rates of each antimicrobial agent was less than 32%.Conclusion The common pathogens of otitis media in preschool children wereStreptococcus pneumoniae,Staphylococcus aureus, and Pseudomonas aeruginosa. However, different bacteria had different drug resistance. Thus, rational use of antibacterial drugs is the key to control infections.
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AIM: To study a method of determining ginsenoside Rg1 and Rb1,notoginsenoside R1 contents in Tiaojing Yangyan Capsule(Radix Astragali,Fructus Ligustri Lucidi,etc.). METHODS: HPLC was used to determine ginsenoside Rg1 and Rb1,notoginsenoside R1 contents. RESULTS: The average recoveries were 99.03% for ginsenoside Rg1(RSD=1.59%),98.95% for ginsenoside Rb1(RSD=1.40%),99.18% for notoginsenoside R1(RSD=1.97%) respectively n=6. CONCLUSION: The method is simple,sensitive and precise.It can be used for the determination of ginsenoside Rg1 and Rb1,notoginsenoside R1 in Tiaojing Yangyan Capsule.
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AIM: To study a method of determing ginsenoside Rg_1 and Rb_1,notoginoside R_1 contents in Xuesaitong Enteric Dripping Pill. METHODS: HPLC was used to determine gingsenoside Rg_1 and Rb_1 notoginse-(noside) R_1 contents. RESULTS: The average recoveries were 100.35% for ginsenoside Rg_1(RSD=1.34%),(102.01%) for ginsenoside Rb_1(RSD=1.48%),100.13% for notoginsenoside R_1(RSD=1.78%),n=6),respectively. CONCLUSION: The method is simple,senstive and precise.It could be used for the determination of ginsenoside Rg_1 and Rb_1,notoginsenoside R_1 contents in Xuesaitong Enteric Dripping Pill.